Recent Publications:

S. Park, L. Wanna, M.E. Johnson and D.L. Venton (2000) "A mass spectrometry screening method for antiaggretory activity of proteins covalently modified by combinatorial library members: application to sickle hemoglobin," Journal of Combinatorial Chemistry, 2, 314-317. (Abstract)

S. Park, M.E. Johnson and L. W.-M. Fung (2000) "NMR analysis of secondary structure and dynamics of a recombinant peptide from the N-terminal region of human erythroid -spectrin," FEBS Letters, 485, 81-86. (Abstract)

S. Park, S. Mehboob, B.-H. Luo, M. Hurtuk, M.E. Johnson and L. W.-M. Fung (2001) "Molecular studies of the erythrocyte spectrin tetramerization region," Cellular and Molecular Biology Letters, 6, 571-585. (Abstract)

J. Cui, F. Marankan, W.T. Fu, D. Crich, A. Mesecar, and M.E. Johnson (2002) "An Oxyanion-Hole Selective Serine Protease Inhibitor in Complex with Trypsin," Bioorganic & Medicinal Chemistry, 10, 41-46. (Abstract)

S. Park, M.E. Johnson and L.W.-M. Fung (2002) "NMR Studies of Mutations at the Tetramerization Region of Human Alpha Spectrin," Blood, 100, 283-288. (Abstract)

S.Park, B.L. Hayes, F. Marankan, D.C. Mulhearn, L. Wanna, A.D. Mesecar, B.D. Santarsiero, M.E. Johnson, D.L. Venton (2003) "Regioselective Covalent Modification of Hemoglobin in Search of Antisickling Agents," Journal of Medicinal Chemistry, 46, 936-953. (Abstract)

J. Cui, D. Crich, D. Wink, M. Lam, A.L. Rheingold, D.A. Case, W.T. Fu, Y. Zhou, M. Rao, A.J. Olson, and M.E. Johnson (2003) "Design and Synthesis of Highly constrained Factor Xa Inhibitors: Amidine-Substituted Bis(benzoyl)-[1,3]-diazepan-2-ones and Bis(benzylidene)-Bis(gem-dimethyl)cycloketones," Bioorganic & Medicinal Chemistry, 11 (16), 3379-3392. (Abstract)

S. Park, M.S. Caffrey, M.E. Johnson and L.W.-M. Fung (2003) "Solution Structural Studies on Human Erythrocyte Alpha Spectrin Tetramerization Site," Journal of Biological Chemistry, 278, 21837-21844. (Abstract)

S. Mehboob, J. Jacob, M. May, L. Kotula, P. Thiyagarajan, M.E. Johnson and L. W.-M. Fung (2003) "Structural Analysis of the ?N-Terminal Region of Erythroid and Non-Erythroid Spectrins by Small Angle X-Ray Scattering," Biochemistry, 42(49), 14702-14710 (Abstract)