BioE 505: NanoBioTechnology

University of Illinois at Chicago
Department of BioEngineering
Spring Semester 2008

Class Schedule: Tuesdays & Thursdays, 3:30 pm - 4:45 pm,

Class Meeting Rm: Room 236 SEO Building

Call No. 26858 LCD (4 Credit Hours)
Prerequisite(s): Consent of the instructors.
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COURSE CONTENTS:

MAJOR TOPICS: (HRS).

  • Fabrication of Nanoscale Structures for Applications in BioEngineering (3.0)

  • Fundamentals of Nanofabrication (3.0)

  • Nanoscale Markers: Synthesis and Uses (4.0)

  • Fundamental Properties Underlying the Design and Uses of Nanostructures in BioEngineering(12.0)
    - Thermodynamics and statistical mechanics of small bio systems
    - Transport phenomena (momentum, heat & mass transfer) in nanobio systems
    - Monte Carlo simulation methods for nanobio systems
    - Molecular dynamics simulation methods for nanobio systems
    - Computer based simulations and optimizations for nanobio systems
    - Phase transitions in nanobio systems

  • Nanoscale Sensors for Applications in BioEngineering: Current Successes and New Concepts (3.0)

  • Fundamental Properties of Biomolecules that are Foundational to Understanding Integrated Nanostructure-Biostructure Complexes and to Drug Delivery (8.0)
    - Nanobio systems intermolecular forces and potentials.
    - Positional assembly of biomolecules.
    - Molecular self-assembly of biomolecules.
    - Dynamic combinatorial chemistry / Dynamic combinatorial library for drug design.
    - Biomolecular building blocks, protein-nanoparticle attachment.
    - Drug delivery - drug targeting - gene therapy.

  • Integrating Manmade Nanostrcutures with Biological Structures including Biomolecules (4.0)
    - Monitoring Biomolecular Processes
    - Altering and Controlling Biomolecular Processes

  • Presentations/Examinations (8.0)

  • TOTAL NUMBER OF HOURS: (45.0)
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    RECOMMENDED BOOKS:

    1. PRINCIPLES OF NANOTECHNOLOGY - Molecular-Based Study of Condensed Matter in Small Systems, by G Ali Mansoori, (World Scientific Pub. Co, 2005).

    2. BIOLOGICAL NANOSTRUCTURES AND APPLICATIONS OF NANOSTRUCTURES IN BIOLOGY: Electrical, Mechanical & Optical Properties, by Michael A. Stroscio and Mitra Dutta, editors, (Kluwer Academic Publishers, 2004)