
P. gingivalis P. intermedia
Tissue
Destructive Factors
Toxic factors:
Ammonia + +
Butyric
acid + -
Propionic
acids + -
Endotoxin Weak Weak
LPS
bone resorption + +
Epitheliotoxin + +
Fibroblast
growth inhibitor + +
Fibronectin
degradation + ?
Indole + +
And
both organisms produce a large number of tissue
destructive factors including ammonia, butyric acid, propionic acids, Endotoxin, which in
turn causes
bone resorption, an Epitheliotoxin, Fibroblast growth inhibitor,
Fibronectin degradating substance, and Indole.
Sound