Exit
Actinobacillus actinomycetemcomitans
Virulence
Factors of A. a.
FACTOR ACTION
Leukotoxin Kills leukocytes
Immunosuppressive
Factor Suppresses immune response
Catalase Destroys peroxides
Superoxide
dismutase Destroys the
superoxide radical
A.a. has quite a few
potential virulence
mechanisms. Most important among these is
its production
of a very rapidly acting
leukotoxin. It also produces a factor that suppresses the immune response. In addition it produces catalase and superoxide dismutase.
