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Actinobacillus  actinomycetemcomitans
Virulence Factors of A. a.
FACTOR ACTION
Several Inhibit fibroblasts endothelial cells & epithelial cell activities
Unknown Tissue invasion
Several factors inhibit fibroblasts, endothelial cells, and epithelial cell activities.
A.a. is also one of a small number of organisms that has been shown to invade the periodontal tissues using an unknown factor.
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