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Dana Foundation: Program in the Neuroimmunology of Brain Infections and Cancers

Program Summary

The Dana Foundation is pleased to announce a call for proposals for its Neuroimmunology program, focusing on brain infections and cancers. Individual grants will total up to $200,000, payable over three years. Specifically, the Foundation is inviting studies of 1) immune-based therapies for primary brain tumors, and for metastases to the brain of other cancers; 2) immune responses to infections in the brain, including but not limited to viral encephalitis, meningitis, cerebral malaria, and prion diseases, and 3) how immune functions are carried out and modified in the brain.  Please note that due to financial constraints, selection this year will be extremely competitive with fewer than 10 percent of preliminary proposals likely to receive funding.

The following are examples of the areas of focus:
  • Exploring ways to stimulate immune cell recognition and attack of primary brain tumors and metastases.
  • Measuring responses to therapeutic vaccines or other immunotherapies for treating brain tumors.
  • Determining ways to prevent and defend against viral infections in the brain.
  • Examining ways to treat infections in the brain, including cerebral malaria.
  • Characterizing the roles of immune cells in normal brain and how these functions are modified under abnormal brain conditions.

While in recent years there have been advances in the field of Neuroimmunology, clinical advances in brain infections and cancers, and in understanding immune functions in the brain require new ideas and approaches. This program focuses on clinical studies in humans or human tissues. Animal studies that are directly relevant to human disease, but not ready for application to studies of humans or human tissues, will also be considered. Proposals for research that can be supported through clinical income should not be submitted.  

Preliminary proposals received by the April 1 deadline will be considered for further development. Applicants will be informed within approximately eight weeks from receipt of proposals whether they are being invited to prepare full proposals. Selected grants will be funded starting October 2009.

Eligibility:
Investigators at institutions that are affiliated with a medical school are eligible to apply only through their affiliated medical school. Projects involving collaborations with NIH intramural researchers or industry scientists are acceptable. Emphasis is placed on providing support to faculty tenure track researchers who are early in their career, at the assistant professor level, or early in their associate professor career. Established researchers pioneering efforts in brain infections and cancers, however, are also eligible to apply. Post-doctoral fellows are not eligible.

UIC is restricted to one application.

Additional Information 
http://www.dana.org/grants/detail.aspx?id=4522

Deadlines


UIC Internal Letter of Intent (mandatory) February 4, 2009
UIC Internal Competition TBD
Preliminary Proposals April 1, 2009

Letter of Intent Instructions

  • By submitting this form, applicant attests that s/he has read and meets the sponsor's eligibility criteria for this program. The LOI can be emailed to RDS@uic.edu, Attn: Chang Lee.  
  • OVCR may reserve submission slots for previously submitted but unfunded proposals that received highly competitive ratings from the external sponsor.    These will be evaluated on a case-by-case basis by the Vice Chancellor. For consideration, scanned copies of your complete reviews (not just summary) must be included with LOI.

LOI form: http://tigger.uic.edu/depts/ovcr/research/funding/forms/0600.doc

Depending upon the number of LOIs submitted, OVCR might be required to facilitate an internal peer review process to select UIC’s submission(s) to this program. White paper instructions will be issued to those submitting LOIs, if necessary.    

Please contact Chang Lee at clee10@uic.edu or 6-1961 with any questions.

 

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