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NIH - Cancer Target Discovery and Development (CTDD) Network (U01)
RFA-CA-11-010
Program Summary
The purpose of this Funding Opportunity Announcement (FOA) and the entire Cancer Target Discovery and Development (CTDD) initiative is to promote innovative research on high throughput approaches to the discovery and characterization of new cancer targets and their modulators. Projects resulting from this FOA are expected to bridge the gap between the enormous volumes of data generated by the comprehensive molecular characterization of a number of cancer types and the ability to use these data for the development of human cancer therapeutics. Applicants must propose research projects focused on high-throughput identification and/or characterization of potential targets for cancer therapy, and/or the identification of small molecules that modulate validated cancer targets. Proposed projects are expected to combine in-depth mining of large-scale genomic data, systems biology analyses and/or experimental approaches to provide initial characterization of functional significance. This characterization may involve the studies of modulation/perturbation of the potential targets (or target combinations) using, e.g., small molecules and/or oligonucleotides. Development and/or improvement of technologies serving the main goals of the project may also be proposed. In addition to conducting individual research projects, the CTDD awardees will also be expected to contribute to trans-Network activities, including participation in joint pilot research projects.
UIC is restricted to one application.
Additional Information
http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-11-010.html
| UIC Internal Notice of Intent (Required) | June 14, 2011 |
| UIC Internal Competition (If necessary) | N/A |
| Sponsor Letter of Intent | July 22, 2011 |
| Sponsor Application | August 22, 2011 |
Letter of Intent
OVCR may reserve submission slots for previously submitted but unfunded proposals that received highly competitive ratings from the external sponsor. These will be evaluated on a case-by-case basis by the Vice Chancellor. For consideration, scanned copies of your complete reviews (not just summary) must be included with LOI.
Depending upon the number of LOIs submitted, OVCR might be required to facilitate an internal peer review process to select UIC’s submission(s) to this program. White paper instructions will be posted if necessary.
eLOI Form & Instructions – Adobe Acrobat Requirements
- Download the file directly to your computer or to a disk, right click on the link, then select "save link as" or "save target as" from the dropdown options.
- Open eLOI.
- Position the hand pointer inside a form field and click.
- To accept the field change and go to the next field, press Tab or use your mouse to click on the next form field.
- To accept the field change and go to the previous field, press Shift + Tab or use your mouse to click on the previous form field.
- Complete the form fields.
- After completing the form, click “Save” then click “Submit to RDS@uic.edu”.
Letter of Intent (LOI): eLOI Form (Fillable PDF*)
*Please note:
- Fields highlighted in red are required to successfully submit the form.
- Do not print then submit scanned version of e-LOI via email.
Please contact Tony Halford at ahalford@uic.edu or 6-7036 with any questions.
If an authorized principal investigator is not listed above, please consider the limited competition still open. Contact RDS@uic.edu for further information. |
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