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Silvio O. Conte Digestive Diseases Research Core Centers (P30) RFA-DK-09-005
Program Summary
The objective of the Silvio O. Conte Digestive Diseases Research Core Centers is to bring together, on a cooperative basis, basic science and clinical investigators to enhance the effectiveness of their research related to digestive and/or liver diseases and their complications. A core center must be an identifiable unit within a single university medical center or a consortium of cooperating institutions, including an affiliated university. An existing program of excellence in biomedical research in the area of digestive and/or liver diseases is a prerequisite for applying. This research must be in the form of NIH research projects, program projects, or other peer-reviewed research that is already funded at the time of submission of a center grant application. Close cooperation, communication, and collaboration among all involved personnel of various professional disciplines are the ultimate objectives.
Centers are encouraged to include a clinical component. This clinical component may exist as a stand-alone component or as a part of a core, such as the Administrative Core. Besides leading to a better understanding of the etiology and natural history of disease, clinical components might provide biostatistics support; enhance clinical study design; foster collaboration among researchers; aid in recruitment of subjects for clinical studies; support epidemiological studies in areas of digestive and/or liver diseases; or provide modest funding for tissue, DNA, or serum storage. In addition, a clinical component may help effectively address NIH policies concerning women, children, and ethnic minority population participation in clinical studies.
Two other types of activities also may be supported with center funding: a Pilot and Feasibility (P/F) program and an Enrichment Program. The P/F program provides modest support for new initiatives or feasibility research studies. This program is directed at new investigators, at investigators established in other research disciplines with expertise that may be applied to digestive or liver disease research, and, occasionally, at investigators already working in digestive or liver disease research who wish to make a substantial change in the direction of their work.
The DDRCC must have a central focus of research investigation. The central focus must be a gastrointestinal disease, group of diseases, or functional studies relating to digestive or liver diseases. At least half of the research must relate to this central focus. Examples of a gastrointestinal disease-related central focus of research investigation include, but are not limited to, inflammatory bowel disease, functional bowel disorders, pancreatic disease, liver disease, pediatric gastrointestinal disease, and AIDS in gastrointestinal disease. Examples of functional studies as the central focus include, but are not limited to, gastrointestinal motility, gastrointestinal hormones, or gene therapy for digestive diseases. Applicants should consult with NIDDK staff concerning plans for the development of the center and the organization of the application.
Award Details
The total project period for an application submitted in response to this funding opportunity may not exceed five years. Direct costs are limited to $750,000 per year.
Additional Information
http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-09-005.html
Deadlines
| UIC Internal Letter of Intent (mandatory) | June 17, 2009 |
| UIC Internal Competition | TBD |
| Sponsor Letter of Intent | October 12, 2009 |
| Sponsor Full Proposals | November 9, 2009 |
Letter of Intent Instructions
- By submitting this form, applicant attests that s/he has read and meets the sponsor's eligibility criteria for this program. The LOI can be emailed to RDS@uic.edu, Attn: Chang Lee.
- OVCR may reserve submission slots for previously submitted but unfunded proposals that received highly competitive ratings from the external sponsor. These will be evaluated on a case-by-case basis by the Vice Chancellor. For consideration, scanned copies of your complete reviews (not just summary) must be included with LOI.
LOI form: http://tigger.uic.edu/depts/ovcr/research/funding/forms/0600.doc
Depending upon the number of LOIs submitted, OVCR might be required to facilitate an internal peer review process to select UIC’s submission(s) to this program. White paper instructions will be issued to those submitting LOIs, if necessary.
Please contact Chang Lee at clee10@uic.edu or 6-1961 with any questions.
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