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Dana Foundation Program in the Neuroimmunology of Brain Cancers and Infections

Internal Competition Completed

Principal Investigator Selected:

  • Douglas Feinstein, Research Professor, Anesthesiology, College of Medicine

Program Description:


The Dana Foundation is pleased to announce a call for proposals for its Neuroimmunology program, focusing on brain cancers and infections. Individual grants will total up to $200,000, payable over three years. Specifically, the Foundation is inviting studies of:
  1. immune-based therapies for primary brain tumors, and for metastases to the brain of other cancers;
  2. immune responses to infections in the brain, including but not limited to viral encephalitis, meningitis, cerebral malaria, and prion diseases; and
  3. how immune functions are carried out and modified in the brain. 

Please note that due to financial constraints, selection this year will be extremely competitive with fewer than 10 percent of preliminary proposals likely to receive funding. 

The following are examples of the areas of focus:
  • Exploring ways to stimulate immune cell recognition and attack of primary brain
      tumors and metastases.
  • Measuring responses to therapeutic vaccines or other immunotherapies for treating
      brain tumors.
  • Determining ways to prevent and defend against viral infections in the
      brain.
  • Examining ways to treat infections in the brain, including cerebral malaria.
  • Characterizing the roles of immune cells in normal brain and how these functions
      are modified under abnormal brain conditions.

While in recent years there have been advances in the field of Neuroimmunology, clinical advances in brain infections and cancers, and in understanding immune functions in the brain, require new ideas and approaches. This program seeks such new ideas and ways to test them.

This program focuses on clinical studies in humans or human tissues.  Animal studies that are directly relevant to human disease, but not ready for application to studies of humans or human tissues, will also be considered.  Proposals for research that can be supported through clinical income should not be submitted.  

Eligibility:
Each U.S. medical school dean, and each president of the few selected biomedical research institutions that have been invited by letter, may nominate one proposal. Investigators at institutions that are affiliated with a medical school are eligible to apply only through their affiliated medical school, by submitting an application to the medical school dean. Projects involving collaborations with NIH intramural researchers or industry scientists are acceptable.  Emphasis is placed on providing support to faculty tenure track researchers who are early in their career, at the assistant professor level, or early in their associate professor career.  Established researchers pioneering efforts in brain infections and cancers, however, are also eligible to apply. Post-doctoral fellows are not eligible.

UIC is restricted to one application from the College of Medicine.

Additional Information 

http://www.dana.org/grants/detail.aspx?id=4522

Deadlines


UIC Internal Letter of Intent (Mandatory)

January 6, 2010

UIC Internal Competition

January 14, 2010

Sponsor Preliminary Proposal   

January 19, 2010, noon

Sponsor Full Proposals

By Invitation

Letter of Intent Instructions

  • By submitting this form, applicant attests that s/he has read and meets the sponsor's eligibility criteria for this program. The LOI can be emailed to RDS@uic.edu, Attn: Chang Lee.
  • OVCR may reserve submission slots for previously submitted but unfunded proposals that received highly competitive ratings from the external sponsor. These will be evaluated on a case-by-case basis by the Vice Chancellor. For consideration, scanned copies of your complete reviews (not just summary) must be included with LOI.
  • Depending upon the number of LOIs submitted, OVCR may be required to facilitate an internal peer review process to select UIC’s submission(s) to this program. Based on the response to this program in previous years, we anticipate that an internal peer review process (Internal Limited Competition) will be required.

LOI form: http://tigger.uic.edu/depts/ovcr/research/funding/forms/0600.doc

Please contact Chang Lee at clee10@uic.edu or 6-1961 with any questions.

If an authorized principal investigator is not listed above, please consider the limited competition still open. Contact RDS@uic.edu for further information.

 

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