Research @ U I C

To complete a form:

Use the table below to determine which forms to complete. Then, use these instructions and the UIC IBC Policy as guidelines.

Rules:

For all research involving animals, appropriate ACC forms must be completed and ACC approval must be obtained prior to beginning work with animals.

For any research involving a select agent, contact EHSO (312-996-7411) to complete registration requirements. Work may only begin following select agent and IBC approval.

For all research involving human cells or tissue, bloodborne pathogen training must be completed on an annual basis. Verification of training will be required prior to final IBC approval for personnel listed in Appendix 1 who will be working with human cells or tissue or other bloodborne pathogens. See the education and training schedule.

For all research involving the shipping or receiving of biological hazards by air, IATA shipping and receiving training must be completed by at least one member of the laboratory listed on Appendix 1. For all research involving shipping or receiving of biological hazards by ground, DOT shipping and receiving training must be completed by at least one member of the laboratory listed on Appendix 1. Please see education and training for additional information.

If your research involves

Complete

Work may begin

Category III rDNA, with all work conducted at BSL1,

Form A, Appendix 1, & BSL1 Biosafety Manual

simultaneously with protocol submission.

Category III rDNA, with at least some work conducted at BSL2

Form A, Appendix 1, & BSL2 Biosafety Manual

following IBC approval.

Category II rDNA, with all work conducted at BSL1,

Form A, Appendix 1, & BSL1 Biosafety Manual

following IBC approval.

Category II rDNA, with at least some work conducted at BSL2

Form A, Appendix 1, & BSL2 Biosafety Manual

following IBC approval.

Category II rDNA, with at least some work conducted at BSL3

Form A, Appendix 1, & Contact IBC office for information on BSL3 Biosafety Manual Requirements

following IBC approval.

Category I rDNA involving deliberate transfer of a drug resistant trait to microorganisms not known to acquire this trait naturally, if such acquisition could compromise the use of the drug to control disease agent in humans, veterinary medicine or agriculture,

Form A, Appendix 1, & Contact IBC office for initial determination of Biosafety Level, Biosafety Manual requirements, and for Coordination of submission to OBA

following NIH Director, RAC and IBC approvals.

Category I rDNA involving cloning of toxic molecules with LD 50 of less than 100 nanograms per kg of body weight,

Form A, Appendix 1, & Contact IBC office for initial determination of Biosafety Level, Biosafety Manual requirements, and for Coordination of submission to OBA

following NIH/OBA and IBC approvals.

Category I rDNA involving cloning of toxic molecules with LD 50 of greater than 100 nanograms, but less than 100 micrograms per kg of body weight,

Form A, Appendix 1 & Contact IBC office for initial determination of Biosafety Level, Biosafety Manual requirements, and for Coordination of submission to OBA

following NIH/OBA and IBC approvals.

Category I rDNA involving deliberate transfer of recombinant DNA, or DNA or RNA derived from recombinant DNA into one or more human subjects,

Form D & Appendix 1

following NIH/OBA, RAC, IRB, and IBC approvals.

an infectious agent (w/o rDNA), with work conducted at BSL2

Form B, Appendix 1, & BSL2 Biosafety Manual

following IBC approval.

a toxin, with work conducted at BSL2

Form B, Appendix 1, & BSL2 Biosafety Manual

following IBC approval.

an infectious agent (w/o rDNA), with work conducted at BSL3

Form B, Appendix 1, & Contact IBC office for information on BSL3 Biosafety Manual Requirements