Editor-in-Chief: Elliot R. Kaufman, Ph.D.
University of Illinois College of Medicine, Chicago
Associate Editors:
Mario Capecchi, University of Utah, Salt Lake City
Yoshio Okada, Osaka University, Japan
Frank Ruddle, Yale University, New Haven, CT
Editorial Board:
W. French Anderson, University of Southern California, Los Angeles
Raghbir Athwal, New Jersey Medical School, Newark
Arthur Beaudet, Baylor College of Medicine, Houston, TX
Helen Blau, Stanford University School of Medicine,CA
Walter Bodmer, Imperial Cancer Research Fund Laboratories, London, UK
Thomas Caskey, Baylor College of Medicine, Houston, TX
Lawrence Chasin, Columbia University, New York, NY
Francis Collins, National Center for Human Genome Research, Bethesda, MD
Franklin Costantini, Columbia University, New York, NY
Carlo Croce, Fels Institute for Cancer Research and Molecular Biology, Philadelphia, PA
Gretchen Darlington, Baylor College of Medicine, Houston, TX
Albert B. Deisseroth, M.D. Anderson Cancer Center, Houston, TX
R.E. Keith Fournier, Fred Hutchinson Cancer Research Center, Seattle, WA
Robert Fraley, Monsanto Company, St. Louis, M0
Uta Francke, Stanford University Medical Center, CA
Theodore Friedmann, University of California, San Diego
James Gusella, Massachusetts General Hospital, Boston
Dean Hamer, National Cancer Institute, Bethesda, MD
Mary Harper, Gen-Probe, San Diego, CA
Morgan Harris, University of California, Berkeley
David Housman, Massachusetts Institute of Technology, Cambridge
Peter Howley, National Cancer Institute, Bethesda, MD
Haig Kazazian, Johns Hopkins Hospital, Baltimore, MD
Hilary Koprowski, The Wistar Institute, Philadelphia, PA
Louis Kunkel, Children's Hospital Medical Center, Boston, MA
John Littlefield, Johns Hopkins University School of Medicine, Baltimore, MD
Barbara Migeon, Johns Hopkins University School of Medicine, Baltimore, MD
Dusty Miller, Hutchinson Cancer Research Center, Seattle, WA
T.K. Mohandas, UCLA School of Medicine, Torrance, CA
Richard Mulligan, Massachusetts Institute of Technology, Cambridge
Susan Naylor, University of Texas, San Antonio
David Patterson, Eleanor Roosevelt Institute for Cancer Research, Denver, CO
Theodore Puck, University of Colorado Medical Center, Denver, CO
Walter Schaffner, Universitat Zurich, Switzerland
Matthew Scharff, Albert Einstein College of Medicine, Bronx, NY
Immo Scheffler, University of California, San Diego
Thomas Shows, Roswell Park Memorial Institute, Buffalo, NY
Louis Siminovitch, University of Toronto, Canada
Larry H. Thompson, University of California, Livermore
Shirley Tilghman, Princeton University, NJ
Inder Verma, Salk Institute, San Diego, CA
James M. Wilson, University of Pennsylvania Medical Center, Philadelphia
Savio Woo, Baylor College of Medicine, Houston, TX
About the journal
An authoritative resource in this rapidly-evolving field during the last two decades, Somatic Cell and Molecular Genetics continues to publish the latest advances in cellular and molecular genetics of higher eukaryotic systems. Keeping pace with current trends in research, the journal has expanded its scope to include the emerging areas of human gene therapy and the molecular biology of inherited diseases. The editorial board of distinguished national and international researchers active in these areas bring their considerable expertise and insightful guidance to the editorial process.
Original articles focus on studies with animal and plant cells in
- gene expression and regulation
- gene transfer into cultured cells or embryos
- gene isolation
- gene mapping
- genetic recombination
- mutation
- chromosome replication
- the genetics of subcellular organelles
- gene therapy
- molecular basis of human disease.
Other areas covered are cell differentiation, malignant transformation, cell-virus interactions, X chromosome inactivation, cell cycle regulation, cell membranes, nuclear transfer, blastomere aggregation, immunogenetics, animal or plant cell culture, and cell fusion.
Somatic Cell and Molecular Genetics will be a much-consulted addition to reference collections serving cell and developmental biologists, molecular biologists, virologists, immunologists, and others working in allied fields.
Somatic Cell and Molecular Genetics is abstracted or indexed in Beck Medical Information, Biological Abstracts, Chemical Abstracts, Current Contents, Exerpta Medica, Index Medicus, International Abstracts of Biological Sciences, Referativnyi Zhurnal and Science Citation Index.
Representative articles on gene transfer and human disease from recent issues:
- Targeting Vector Configuration and Method of Gene Transfer Influence Targeted Correction of the APRT Gene in Chinese Hamster Ovary Cells, Rodney S. Nairn, Gerald M. Adair, Thomas Porter, Sandra L. Pennington, Debra G. Smith, John H. Wilson, and Michael M. Seidman.
- Introduction of YACs Containing a Putative Mammalian Replication Origin into Mammalian Cells Can Generate Structures that Replicate Autonomously, Genevieve H. Nonet and Geoffrey M. Wahl.
- New Vector for Transfer of Yeast Artificial Chromosomes to Mammalian Cells, David Markie, Jiannis Ragoussis, Gabriele Senger, Andrew Rowan, David Sansom, John Trowsdale, Denise Sheer, and Walter F. Bodmer.
- Direct DNA Injection into Mouse Tongue Muscle for Analysis of Promoter Function In Vivo, T. Prigozy, K. Dalrymple, L. Kedes, and C. Shuler.
- DNA Methylation of the Fragile X Locus in Somatic and Germ Cells during Fetal Development: Relevance to the Fragile X Syndrome and X Inactivation, Shengyuan Luo, .J. Courtland Robinson, Allan L. Reiss, and Barbara R. Migeon.
- Sensitivity of Roberts Syndrome Cells to Gamma Radiation, Mitomycin C, and Protein Synthesis Inhibitors, David J. Van Den Berg and Uta Francke.
- Neurofibromatosis Type 1 Gene Product (Neurofibromin) Associates with Microtubules, Paula E. Gregory, David H. Gutmann, Anna Mitchell, Soochul Park, Mark Boguski, Tyler Jacks Deborah L. Wood, Richard Jove, and Francis S. Collins.
- Mutational Analysis of a Patient with a Variant Form of Gaucher Disease Caused by SAP-2 Deficiency, Mohammad A. Rafi, Gregory de Gala, Xun-ling Zhang, and David A. Wenger.
- Complementation of DNA Repair Defect in Xeroderma Pigmentosum Cells of Group C by Transfer of Human Chromosome 5, Gurusinder Pal Kaur and Raghbir S. Athwal.
- Adenovirus-Mediated Correction of the Genetic Defect in Hepatocytes from Patients with Familial Hypercholesterolemia, Karen Kozarsky, Mariann Grossman, and James M. Wilson.
- Complementation Analysis of Chediak-Higashi Syndrome: The Same Gene May Be Responsible for the Defect in All Patients and Species, Charles M. Perou and Jerry Kaplan.
- Hepatic Gene Therapy: Efficient Retroviral Mediated Gene Transfer into Rat Hepatocytes In Vivo, Tadeusz M. Kolodka, Milton Finegold, and Savio L. C. Woo.
- Structure and Expression of the Huntington's Disease Gene: Evidence Against Simple Inactivation Due to an Epanded CAG Repeat, Christine M. Ambrose, Mabel P. Duyao, Glenn Barnes, Gillian P. Bates, Carol S. Lin, Jayalakshmi Srinidhi, Sarah Baxendale, Holger Hummerich, Hans Lehrach, Michael Altherr, John Wasmuth, Alan Buckler, Deanna Church, David Housman, Mary Berks, Gos Micklem, Richard Durbin, Alan Dode, Andrew Read, James Gusella, and Marcy E. MacDonald.
- Generation of a Mouse Model for Citrullinemia by Targeted Disruption of the Argininosuccinate Synthetase Gene, Gerald Patejunas, Allan Bradley, Arthur L. Beaudet, and William E. O'Brien.
The editorial board of Somatic Cell and Molecular Genetics welcomes the opportunity to review your original manuscript. Please see the Instructions to Authors provided below and submit your manuscript to:
Elliot R. Kaufman, Ph.D.
Editor-in-Chief
Department of Molecular Genetics (M/C 669)
University of Illinois College of Medicine
900 South Ashland Avenue
Chicago, Illinois 60607-7170
Telephone: (312) 996-6975
FAX: (312) 355-1475
email: erk@uic.edu
- Submission is a representation that the manuscript has not been published previously and is not currently under consideration for publication elsewhere. A statement transferring copyright from the authors (or their employers, if they hold the copyright) to Plenum Publishing Corporation will be required before the manuscript can be accepted for publication. The Editor will supply the necessary forms for this transfer. Such a written transfer of copyright, which previously was assumed to be implicit in the act of submitting a manuscript, is necessary under the U.S. Copyright Law in order for the publisher to carry through the dissemination of research results and reviews as widely and effectively as possible.
- Type double-spaced, and submit the original and two copies (including copies of all illustrations and tables). The title page should include the academic affiliation of each author, a brief running title, and the full mailing address and telephone number of the one author who will receive the proofs.
- An abstract of not more than 150 words must be included.
- Original papers should be in English and should be divided into the following sections: Introduction, Materials and Methods, Results, Discussion, and Literature Cited. Within a section, do not use more than one level of subheadings.
- References should be cited in the text by number only and in numerical order. The style of the "Literature Cited" section should conform to the style that is consistently used in the journal. References to unpublished work and to manuscripts in preparation should be made in the text only and should not be included in the "Literature Cited" section.
- Tables should be numbered with Arabic numerals and should be so referred to in the text. Each table should be typed on a separate sheet of paper and should have a brief descriptive title.
- Figures (photographs, drawings, diagrams, and charts) should be numbered in one consecutive series of Arabic numerals. Photographs should be large, high-quality, glossy prints, showing high contrast. Photographs should not be mounted unless a composite grouping is required. Identify figures on the back with author's name and number of the illustration. Each figure should have an accompanying legend, which should be typed on a separate sheet of paper. Use the legend for explanation of symbols rather than putting such details in figures. Reproduction of illustrations in color is possible by special arrangement, with the total cost, which is significant, borne by the author.
- After a manuscript has been accepted for publication and after all revisions have been incorporated, manuscripts may be submitted to the Editor's Office on personal-computer disks. Label the disk with identifying information-kind of computer used, kind of software and version number, disk format and file name of article, as well as abbreviated journal name, authors' last names, and (if room) paper title. Package the disk in a disk mailer or protective cardboard. The disk must be the one from which the accompanying manuscript (finalized version) was printed out. The Editor's Office cannot accept a disk without its accompanying, matching hard-copy manuscript. Disks will be used on a case-by-case basis-where efficient and feasible.
- The journal makes no page charges. Reprints are available to authors, and order forms with the current price schedule are sent with proofs.
Comments to erk@uic.edu