Alumni
Yan Pan (DNA physical properties, experiment, MS Physics 01)
Mazen Albaghdadi (undergraduate researcher BEng Bioeng 02)
Prateek Gupta (undergraduate researcher BEng Bioeng 02), now in UIC Mech. Eng. PhD program
Caiti Hamill-Thompson (undergraduate researcher BS 00), now in Northwestern U biology PhD program
Tamar Monhait (undergraduate researcher BEng EECS 01)
Ajay Nemani (undergraduate researcher BS 00), now in UIC MD-PhD program
Michael Poirier (chromosome physical properties, experiment PhD 01), now junior faculty at Ohio State University
Abhijit Sarkar (DNA micromanipulation theory PhD 02), now junior faculty at Virginia State University
Lisa Pope, Ph.D. (single chromosome and chromatin fiber micromanipulation), now in biomedical research industry
Sumithra Sankararaman, Ph.D. (theory of single-DNA experiments), now postdoctoral researcher at Washington University, St. Louis MO
Hannah Lazarus (single-DNA experiments, B Eng Bioeng 05), now graduate student at U Cal Irvine
Chee Xiong (chromosome structure and dynamics, M.Eng. Bioeng 05), now Development Associate II at Alexion Pharmaceuticals, Cheshire CT
Dunja Skoko (single-DNA experiments, PhD Physics 06), now postdoctoral researcher at the NIH
Publications (1997-present)
Mitotic chromosome scaffold structure: New approaches to an old controversy
Proc. Natl. Acad. Sci. USA 99, 15855-7 (2002)
Dynamics
of chromosome compaction during mitosis
A.
Sarkar, S. Eroglu, M.G. Poirier, P. Gupta, A. Nemani, J.F. Marko
Exp.
Cell Res. 277, 48-56 (2002)
Theoretical micromechanics of DNA and DNA-protein complexes
A. Sarkar
Ph.D. Thesis, University of Illinois at Chicago (2002)
(Note that sections of this thesis have been separately published
as research papers)
The
bending rigidity of mitotic chromosomes
M.G.
Poirier, S. Eroglu, J.F. Marko
Mol.
Biol. Cell 13, 2170-9 (2002)
Micromechanical
properties of mitotic chromosomes (review)
M.G.
Poirier, J.F. Marko
J.
Muscle Res. Cell. Motil. 23, 409-431 (2002)
Theoretical
models for single-molecule DNA and RNA experiments: from elasticity to
unzipping (review)
S.
Cocco, J.F. Marko, R. Monasson
C.
R. Physique (Paris) 3, 569-584 (2002)
Force
and kinetic barriers to initiation of DNA unzipping
S.
Cocco, R. Monasson, J.F. Marko
Phys.
Rev. E 65, 041907 (2002)
Effect
of internal friction on biofilament dynamics
M.G.
Poirier and J.F. Marko
Phys.
Rev. Lett. 88, 228103-6 (2002)
Reversible
hypercondensation and decondensation of mitotic chromosomes
studied using combined chemical-micromechanical techniques
M.G.
Poirier, T. Monhait, J.F. Marko
J.
Cell. Biochem. 85, 422-34 (2002)
Micromechanical-Biochemical
Studies of Mitotic Chromosome Structure
M.G.
Poirier
Ph.D.
Thesis, University of Illinois at Chicago (2001)
(Note
that sections of this thesis have been separately published
as research papers)
Removal
of DNA-bound proteins by DNA twisting
A.
Sarkar and J.F. Marko
Phys.
Rev. E 64, 061909-061918 (2001)
Force
and kinetic barriers to unzipping of the DNA double helix
S.
Cocco, R. Monasson and J.F. Marko
Proc.
Natl. Acad. Sci. USA 98, 8603-13 (2001)
Short
note on the scaling behavior of communication by 'slithering' on a supercoiled
DNA
J.F.
Marko
Physica
A 296, 289-292 (2001)
Structural
transitions in DNA driven by external force and torque
A.
Sarkar, J.-F. Leger, D. Chatenay and J.F. Marko
Phys.
Rev. E 63, 051903-051912 (2001)
Chromosome
elasticity and mitotic polar ejection force
measured
in living Drosophila embyros by four-dimensional microscopy-based motion
analysis
W.F.
Marshall, J.F. Marko, D.A. Agard and J.W. Sedat
Curr.
Biol. 11, 569-78 (2001)
Probing
chromosome structure using dynamic force relaxation
M.G.
Poirier, S. Eroglu, A. Nemani, P. Gupta and J.F. Marko
Phys.
Rev. Lett. 86 360-3 (2001)
Kinetic
proofreading can explain the supression of supercoiling
of
circular DNA molecules by type-II topoisomerases
J.
Yan, M.O. Magnasco and J.F. Marko
Phys.
Rev. E 63, 031909-031919;(2001)
One-
and three-dimensional pathways for proteins to reach specific DNA sites
N.P.
Stanford, M.D. Szczelkun, J.F. Marko, S.E. Halford
EMBO
J. 19, 6546-57 (2000)
Reversible
and irreversible unfolding of mitotic newt chromosomes by applied force
M.
Poirier, S. Eroglu, D. Chatenay and J.F. Marko, Mol. Biol. Cell. 11, 269-276
(2000)
Kinetic proofreading mechanism for DNA disentanglement by topoisomerases
J.
Yan, M.O. Magnasco and J.F. Marko, Nature 401, 932-935 (1999)
Structural
transformations of a twisted and stretched DNA
J.F.
Leger, J. Robert, L. Bordieu, A. Sarkar, D. Chatenay and J.F. Marko,
Phys.
Rev. Lett. 83, 1066-1069 (1999)
Coupling
of intra- and intermolecular linkage complexity of two DNAs
J.
F. Marko, Phys. Rev. E 59, 900-912 (1999)
RecA
binding to a single double-stranded DNA molecule: a possible role of DNA
conformational fluctuations
J.F.
Leger, J. Robert, L. Bordieu, D. Chatenay and J.F. Marko,
Proc.
Natl. Acad. Sci. USA, 95, 12295 (1998)
Architecture
of a bacterial chromosome (review)
N.
J. Trun and J. F. Marko, American Society for Microbiology News 64, 276
(1998)
Polymer
models of meiotic and mitotic chromosomes
J.
F. Marko and E. D. Siggia, Mol. Biol. Cell 8, 2217 (1997)
Interphase
chromosomes undergo constrained diffusional motion in living cells
W.F.
Marshall, A. Straight, J.F. Marko, J. Swedlow, A. Dernburg, A. Belmont,
A.W. Murray, D.A. Agard DA, J.W. Sedat
Current
Biology 7, 930-9 9 (1997)
External Funding
John Morris Schechtman-Marko
John F Marko, jmarko@uic.edu Department of Physics, MC 273, The University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607-7059 office (312)996-6064, dept. office (312)996-3400, fax (312)996-9016