BIOS 103

LECTURE		LABORATORY / DISCUSSION
TR 3:30-4:45, 250 SES		LABORATORY GUIDE
Dr. Leo Miller		Dr. Alan Molumby
3378 SES		3456 SEL
312-996-2220, leo@uic.edu		312-996-2994, molumby@uic.edu
Office Hour: Tue 2:30-3:30		Office Hour: Thur 10:00-11:00

BIOS 103 (5 credit hours) meets the UIC requirements for Natural Science course distribution credit.

Overview: Basic and clinical research in developmental biology and reproduction have led to remarkable advances which have dramatically changed the way we live. Recent advances in in vitro fertilization and cloning have challenged our long standing views of parenthood, family, and personal identity. We are grappling with the idea of using tissues and organs of human embryos and fetuses for research; they are already being used to treat individuals with neurodegenerative diseases. The production of human embryonic stem cell lines has been accomplished recently and holds unimaginable potential for the repair and replacement of diseased tissues and organs. Rejection of transplanted tissues may be overcome using therapeutic cloning and the production of universal donor tissues. We are on the doorstep of genetically engineering human cells and gene therapy. These advances in genetics, molecular biology and embryology have raised a number of ethical, religious and legal issues which all of us must confront. In this course we will emphasize the basic scientific principles of embryology and reproduction and discuss how they are relevant to confronting these ethical issues. Our goal is to help you to become a critically thinking scientifically literate citizen, ready to make informed decisions about issues related to human development, health and reproduction.

Dr. Miller and invited speakers will give the lectures in one of the new multimedia classrooms - 250 SES. Laboratories are conducted in 3098 SEL and the Discussion in 310 Adams Hall or 204 Taft Hall. Dr. Molumby is in charge of the lab/discussion portion of the course and will be aided by four graduate student teaching assistants: Michael Carr, Kathleen Craft, Holly Dimitropoulos and Dawn Franks. Although you will have different instructors we will work hard to integrate the different parts of the course. We intend that the presentations in the lecture, lab and discussion from different instructors and invited speakers, combined with the text readings, handouts, field trips and computer work, will provide diverse sources of information to facilitate your learning.

Textbook: Biology: Science and Life, 1996. M.R. Cummings, Brooks-Cole Pub. Co. This text will also be used for BioS 104, "Life Evolving", which is offered in Spring Semester. Both BioS 103 and 104 meet the UIC requirements for Natural Science course distribution credit. Biology: Science and Life comes packaged with a collection of recent articles, "Current Perspectives in Biology", designated CP in the reading assignments below. The other reading assignments are from the main textbook. For many topics you will also receive handouts of reading material.

BIOS 103 Homepage: http://www.uic.edu/~leo/bios103.html

WK	DATE	LECTURE TOPIC	READ
1	AUG 22, 24	Introduction, Development, Properties of life, When does life begin, Nature of science, Sexual and asexual reproduction Grading; Internet Report; Race for the Cure or AIDS Walk, Museum of Science and Industry	1-14, 528-530, CP:127-129
		LAB 1: Review of Lab/Discussion , Video
2	AUG 29, 31	Genes, DNA, Mutation, Evolution	138-146, 150-153
		LAB 2: Mitosis, Growth, Development	85-104
		Lecture Notes
3	SEPT 5, 7	Recombinant DNA, Genetic testing, Genetic engineering, Gene therapy	155-160, 166-170
		LAB 3: NO Discussion or Lab - Internet report due Week 4
		Lecture Notes
4	SEPT 12,14	Male reproductive system, spermatogenesis, mitosis and meiosis	532-536
		LAB 4: Meiosis, Recombination, Sexual Reproduction
		Lecture Notes
5	SEPT 19	Structure of the seminiferous epithelium, hormonal regulation of spermatogenesis, pheromones and volmernasal biology	334-341, 493-500
	SEPT 21	EXAM I Test Questions
		LAB 5: Human Mate Choice
6	SEPT 26, 28	Female reproductive system, Oogenesis, development of the follicle and oocyte	537-541
		LAB 6: GeneTherapy, Human Genetic Diversity, Genetic Counseling, Eugenics	CP:36-40
		Lecture Notes
7	Oct 3, 5	Hormonal regulation of follicle growth, ovulation and the menstrual cycle	540-541, CP:130-136
		LAB 7: Debate: Cloning
8	OCT 10	Gender identity: Invited Speaker Dr Timothy Murphy, Department of Medical Education, Medical Humanities Program Head	568
	OCT 12	Development of the male and female reproductive system	549-550
		LAB 8: Sea Urchin Fertilization and Chick Early Development
		Lecture Notes
9	OCT 17, 19	Early human development - fertilization in vivo and in vitro, cleavage, implantation of the embry, organ formation	528-532, 544-551
		LAB 9: Biology of Sexually Transmitted Disease	542-544
10	OCT 24	Early human development, Review	417-418, 551-52
		The scheduled Discussion Sections will be held in the lab for the rest of the term. Please report directly to Lab - 3098 SEL
		LAB 10: Contraception, Sexually Transmitted Diseases; Annann Hong, Rachel Calderon, Bindi Desai, Irene Ortiz, Elizabeth Raigoza, Karen Riley,Trina Thompson UIC Wellness Center , Poster Essay Due (no points if turned in next week)
		Lecture Notes
10	OCT 26	EXAM II Test Questions
11	OCT 31, NOV 2	Cell differentiation, cancer, oncogenes and tumor suppressors	94-95
		Lecture Notes
		LAB 11: Breast Feeding: Invited Speakers, Dr. Marty O'Donnell La Leche League International
12	NOV 7, 9	Breast development, milk production, breast cancer	552, CP:189-193
		LAB 12: Poster Presentations
13	NOV 14,16	Genetic testing for breast cancer. HIV-AIDS.	421-22
		LAB 13: Poster Presentations
14	NOV 21	Stem cells, regeneration and replacement organs.
		Lecture Notes
	NOV 23	Thanksgiving Holiday-No Classes
		LAB 14: NO Discussion or Lab this week
15	Nov 28	Cloning livestock and humans
		Lecture Notes
	Nov 30	EXAM III TEST QUESTIONS
		LAB 15: FINAL GRADE CONFERENCE
Exam Week	WED DEC 6th	3:30 - 4:30 Optional Final Examination, 250SES

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Discussion/Lab Assignments

Lab Guide

Grading